Methods

1.      First Generation of Short Oligonucleotide Sequencing Assay (SOSA):

Fiala, K.A. and Suo, Z.* (2007) Sloppy Bypass of an Abasic Lesion Catalyzed by a Y-family DNA Polymerase. J. Biol. Chem. 282, 8199-8206. (pdf) (SI) [Press Release]

2.      Second Generation of Short Oligonucleotide Sequencing Assay (SOSA):

Taggart, D.J., Camerlengo, T.L., Harrison, J.K., Sherrer, S.M., Kshetry, A.K., Taylor, J., Huang, K., Suo, Z.* (2013) A High-Throughput and Quantitative Method to Assess the Mutagenic Potential of Translesion DNA, Nucleic Acids Research. Volume 41, Issue 8, Pages e96. [Online Access]

(Note: If you need the NGS Position Counter program for analyzing HT-SOSA data, please contact Dr. Zucai Suo)