Welcome to Our Viral Vector and Gene Editing Core Services
Home | Personnel | Services | Resources & Plasmids | Contact Us | How To Order |
Standard Operating Procedures | Biosafety Plan | Molecular Cloning Service | Publications
Whether you are an experienced researcher or just getting started with gene delivery and genome engineering, the Florida Institute for Pediatric Rare Diseases (IPRD) Viral Vector and Gene Editing Core (VVGEC) service is here to help. We offer expert support, custom services, and a friendly, collaborative approach to meet your scientific goals.
The IPRD Viral Vector and Gene Editing Core is a full-service facility specializing in the design, development, and production of viral vectors and gene editing tools. We support research projects of all types and sizes, and our services are available to academic, clinical, and industry partners.
Our team brings extensive expertise in:
Viral vector production (including lentivirus, adeno-associated virus [AAV], adenovirus, and retrovirus)
- CRISPR-based gene editing
- Optogenetics
- Custom protein and antibody engineering
We offer everything from small pilot batches to large-scale vector production, along with consultation and project design support every step of the way.
Core Services Overview
Here are some of the ways we can support your research:
Viral Vector Services
- Design, construction, and cloning of plasmids for gene delivery
- Ready-to-use vector backbones for your gene of interest
- Production of lentivirus, AAV, retrovirus, and adenovirus vectors
- Support for in vitro and in vivo applications
- Flexible production scales: small, mid, or large batches
- Naïve and reporter constructs in both AAV and lentiviral formats
- Robust quality control, including plasmid sequencing and safety testing (e.g., RCR screening for HIV-1–based vectors)
Gene Editing Services
- Custom CRISPR/Cas9 design and validation
- Creation of knockout, knock-in, and conditional models (KO, KI, CKO)
- Generation of genetically modified stable cell lines
- Access to a large library of RNA interference (RNAi) vectors and CRISPR tools for conventional, base, prime, and epigenome editing
Optogenetics
- Access to more than 300 optogenetic vectors from leaders in the field (Karl Deisseroth, Bryan Roth, Ed Boyden, and others)
- Tools to control cell activity with light in complex tissues
- Consultation on vector selection and application design
Protein and Antibody Engineering
- Custom design of antibodies, enzymes, and protein switches
- Engineering of proteins with novel binding or signaling capabilities
- Support from early-stage discovery through stable cell line development
Personalized Project Support
Our team works closely with investigators to design and deliver custom solutions. We provide one-on-one consultations to:
- Recommend appropriate viral vector platforms and gene editing tools
- Select optimal serotypes or pseudotypes for your target tissues or cells
- Help integrate CRISPR tools with transgenic animal models
- Support every step from concept to implementation
Facility and Location
The Viral Vector and Gene Editing Core is located within the Florida Institute for Pediatric Rare Diseases (IPRD) at the FSU College of Medicine in Tallahassee.
Location:
- Suite 3100M and Lab 3310
- 3rd Floor, FSU College of Medicine
- The facility includes separate rooms for cell culture, DNA/virus production, quality control, and support functions, all designed to meet high standards of safety and efficiency.
Why Choose Us?
- State-of-the-art tools and infrastructure
- Expert staff with decades of combined experience
- Flexible, project-tailored services
- Support for both research and translational goals
- Welcoming and collaborative approach
- Competitive, transparent pricing
Get Started
Whether you need a single batch of virus or full-service support for a complex genome editing project, we are here to help.
Contact us today to schedule a consultation, request a quote, or learn more about how our services can accelerate your research.