Instruments

Q Exactive: Staff Operated

Thermo Scientific Q ExactiveTM HF Hybrid Quadrupole-OrbitrapTM Mass Spectrometer combines a segmented quadrupole for high-performance precursor ion selection with a high-resolution, accurate-mass (HR/AM) ultra-high-field Orbitrap mass analyzer to deliver a superior combination of scan speed, resolving power, mass accuracy, spectral quality and sensitivity. Additionally, has Intact Protein Mode for characterizing intact proteins.

Thermo Scientific Q Exactive HF Hybrid Quadrupole-Orbitrap Mass Spectrometer combines a segmented quadrupole for high-performance precursor ion selection with a high-resolution, accurate-mass (HR/AM) ultra-high-field Orbitrap mass analyzer to deliver a superior combination of scan speed, resolving power, mass accuracy, spectral quality and sensitivity. In addition, has Intact Protein Mode for characterizing intact proteins. 

Exploris 480: Staff Operated

Exploris 480

Thermo Scientific Orbitrap Exploris 480  is a quantitative high-resolution, accurate-mass (HRAM) liquid chromatography Mass Spectrometer (LC-MS) consisting of a 1200 bar LC connected to a quadrupole/orbitrap hybrid mass analyzer capable of up to 480,000 resolving power.

 

Xevo TQ-S: Staff Operated

  

Waters Xevo TQ-S UPLC-nESI-Triple Quadrupole is a tandem mass spectrometer that can be used to validate potential biomarkers. The TQ-S can be connected to The Waters Atmospheric Pressure GC/MS with Agilent 7693 Autosampler to analyze volatile and semi-volatile compounds or to the Waters NanoAcquity Ultra Performance Liquid Chromatograph, which uses low flow rates (nL/min) and high pressures (5000-6000 psi) to separate small quantities of proteins. 
 

 

NovaSeq X Plus: Staff Operated

NovaSeq

Illumina NovaSeq X Plus Sequencer is a next-generation sequencer used to determine the sequence of entire genomes (DNA), exomes (Exon), transcriptomes (RNA), miRNomes (miRNA), Cistromes (ChIP-Seq) extremely quickly. More than 52 billion sequencing reads can be generated in less than 48 hours. 

10X Genomics Chromium X: Researcher Operated

10X Controller

10X Genomics Chromium X runs all single cell assays, including new high-throughput assays for Single Cell Immune Profiling and Single Cell Gene Expression. 

 

OFFGEL Fractionator: Researcher Operated

Agilent OFFGEL Fractionator separates proteins according to the pH at which they have no net charge, allowing researchers to simplify protein mixtures before mass spec analysis. 

 

SpeedVac: Researcher Operated

Thermo Scientific Express SC250EXP SpeedVac™ Concentrator System uses centrifugation, vacuum and heat technologies for removing solvents and concentrating samples.

 

Bioanalyzer: Researcher Operated

Agilent 2100 Bioanalyzer is a microfluidic electrophoresis system used to measure the quantity, quality and average size of DNA, RNA or protein in a sample. Accurate sizing of samples intended for sequencing on the HiSeq 2500 can be accomplished with the Bioanalyzer. 

Qubit: Researcher Operated

 

Thermo Scientific Qubit 2.0 is a benchtop fluorometer for quantitation of DNA (dsDNA & ssDNA), RNA and protein. Target-specific fluorescent dyes are used to minimize quantitation of contaminating molecules. This system is more accurate for samples with low quantity particularly for sequencing on the HiSeq 2500. 

NanoVue: Researcher Operated

GE Healthcare NanoVue is a UV/Vis spectrophotometer that measures nucleic acids and proteins with sample volumes as low as 0.5 microliters. Measures: DNA, RNA, Oligonucleotides, Tm Calculation, Cy Dye DNA probe labeling, Protein UV & A280, BCA, Bradford, Lowry, & Biuret.