Epstein-Barr virus LMP1 manipulates the content and functions of extracellular vesicles to enhance metastatic potential of recipient cells

Schematic model of protocol used to treat MCF10A cells with EVs. MCF10A cells were treated with equal number of EVs from either HK1 WT or HK1 LMP1 or equivalent volume of PBS every 24 hrs for 2 days before isolating mRNA for RNA-seq graphic
From the Meckes Lab: Extracellular vesicles (EV) mediate intercellular communication events and alterations in normal vesicle content contribute to function and disease initiation or progression . . .

Learn More