CANCELED "DNA Dynamics Driven Mutagenesis: How DNA Determines Its Copying Errors" - Dr. Hashim Al-Hashimi
Dr. Al-Hashimi’s research focus is the theoretical design and implementation of new NWR experiments for probing the physicochemical properties of biomolecules, with particular interest in RNA and DNA and the proteins and small molecules that bind to them. Dr. Al-Hashimi is the recipient of multiple awards and honors, including the Founder’s Medal in NMR spectroscopy, the Vilcek Prize For Creative Promise in Biomedical Science, and the Agilent Thought Leader Award. Dr. Al-Hashimi’s work on molecular visualization and nucleic acid dynamics was also recognized by Popular Science Magazine, which listed him among the ‘Brilliant 10’ scientists and engineers in USA (2011). In 2009, he co-founded Nymiurm Inc, which is using the methods developed in the Al-Hashimi lab to increase the pace of RNA structure characterization and RNA-targeted drug discovery.
Mutations drive evolution and cause diseases such as cancer. But what causes mutagenesis? In this talk, Dr. Al-Hashimi will advance a new perspective in which the dynamics of the base pairs in the DNA double helix play an important role determining when, where, and to what extent mutations occur.
Florida State University College of Medicine Auditorium