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James M Olcese Ph.D.

James M Olcese Ph.D.

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Dr. Olcese has served as a visiting assistant professor at Marquette University in Milwaukee, Wis., as an assistant professor and associate professor at Rhodes College in Memphis, Tenn., and as a professor and group leader at the Institute for Hormone & Fertility Research at the University of Hamburg Medical School in Hamburg, Germany.


B.S., Biology, Emory University, Atlanta, Ga.

Ph.D., Physiology, Marquette University, Milwaukee, Wis.

Postdoctoral fellow, Department of Anatomy, University of Mainz, Germany


Past member of the Editorial Boards of Journal of Endocrinology and Journal of Pineal Research. Currently Associate Editor for Frontiers in Molecular Neuroscience and Chief Speciality Editor for Frontiers in Endocrinology.


FSU College of Medicine Outstanding Senior Investigator Award (2016);
Innovator Award, FSU Office of Research (2010,2011,2012, 2013, 2014, 2015);
Alexander von Humboldt Research Fellowship - University of Hamburg, Germany (1989-90);
Dean's Award for Outstanding Faculty Research - Rhodes College, Memphis, Tenn. (1987);
Undergraduate Scholarship, Emory University (1971).


Society for Neuroscience USA

European Biological Rhythms Society

Sigma Xi

New York Academy of Science

Society for Research on Biological Rhythms

Endocrine Society

Society for the Study of Reproduction

International Society to Advance Alzheimer Research and Treatment

American Physiological Society

Research Focus

Circadian Physiology (endocrine rhythms, sleep disorders); Neuroendocrine mechanisms (hormonal systems, reproductive function); Alzheimer dementia and melatonin


Beesley S, Olcese J, Saunders C and E.A. Bienkiewicz (2016) Combinatorial treatment effects in a cell culture model of Alzheimer's disease. Journal of Alzheimer’s Disease 55: 1155-1166

O’Neal-Moffitt G.A., Delic V., Bradshaw P.C., and J. Olcese (2015) Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in APPswe/PS1 mice. Molec Neurodegeneration 10: 27-47

Beesley S., Lee J. and J. Olcese (2015) Circadian Clock Regulation of Melatonin MTNR1b Receptor expression in Human Myometrial Smooth Muscle Cells. Molec Human Reproduction 21: 662–671

Beesley S. and J. Olcese (2014) The Clinical Significance of Melatonin Receptors in the Human Myometrium. Fertility and Sterility 102:329-335

O'Neal-Moffitt G., Pilli J., Kumar S.S., and J. Olcese (2014) Genetic deletion of melatonin receptors enhances murine cognitive and motor performance. Neuroscience 277:506-521

Corthell J.T., Olcese J., and P.Q. Trombley (2013) Melatonin in the mammalian olfactory bulb. Neuroscience 261: 74-84.

Olcese J, Lozier S and C. Paradise (2012) Melatonin and the timing of human parturition. Reprod. Sci 20: 168-174

Olcese J. (2012) Circadian aspects of parturition. Molec Cell Endocrinol 349: 62-67.

Dragicevic, N., Copes, N., O'Neal-Moffitt, G., Jin, J., Buzzeo, R., Mamcarz, M., Tan, J., Cao, C., Olcese, J. M., Arendash, G. W., & Bradshaw, P. C. (2011) Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling. J Pineal Res, 51: 75-86.

Dubocovich, M.L., Delagrange, P., Krause, D.N., Sugden, D., Cardinali, D.P. and J. Olcese. (2010) Nomenclature, Classification and Pharmacology of G Protein-Coupled Melatonin Receptor. Pharmacol Rev 62(3): 343-380

Sharkey, J. T., Cable, C., & Olcese, J. (2010) Melatonin sensitizes human myometrial cells to oxytocin in a protein kinase C alpha/extracellular-signal regulated kinase-dependent manner. J Clin Endocrinol Metab, 95(6), 2902-8.

Olcese, J. M., Cao, C., Mori, T., Mamcarz, M. B., Maxwell, A., Runfeldt, M. J., Wang, L., Zhang, C., Lin, X., Zhang, G., & Arendash, G. W. (2009) Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. J Pineal Res, 47(1), 82-96.

Sharkey, J. T., Puttaramu, R., Word, R. A., & Olcese, J. (2009) Melatonin synergizes with oxytocin to enhance contractility of human myometrial smooth muscle cells. J Clin Endocrinol Metab, 94(2): 421-7.

Sikes-Resuehr H.E., Resuehr D. and J. Olcese. (2009) Induction of mPer1 expression by GnRH in pituitary gonadotrope cells involves EGR-1. Molec. Cell. Endocrinol. 311: 120-125