A clinical trial is testing how digital tools, social support, and mindfulness training can help breast cancer survivors become more physically active. The Fit2ThriveMIND study provides participants with a Fitbit and a custom smartphone app designed to support safe, gradual increases in moderate to vigorous physical activity.

The trial, co-led by Bonnie Spring, Ph.D., of the Florida Blue Center for Rural Health Research & Policy, is enrolling 304 post-treatment survivors who are currently inactive. Using the Multiphase Optimization Strategy (MOST) framework, the study evaluates four components — a social support “Buddy,” digital e-coaching, general mindfulness training, and mindfulness techniques specific to exercise — by assigning participants to different combinations of each.

The primary goal is to determine which strategies or combinations lead to meaningful increases in activity at 24 and 48 weeks. The researchers also examine how increased activity affects fatigue, mood, sleep, sedentary behavior, and other health-related outcomes, and test a long-term maintenance approach to help participants sustain behavior changes.

By identifying the most efficient and effective components, Fit2ThriveMIND aims to guide the development of scalable programs that improve the long-term health and quality of life for breast cancer survivors.