Professor of Biomedical Sciences
B.S. Rockhurst University, Kansas City, Missouri
Ph.D. University of Missouri
American Physiological Society
American Microcirculatory Society
American Heart Association
My research focuses on cardiovascular adaptations to aging and exercise training. Specifically, I am interested in adaptations of the microcirculation in the heart and skeletal muscle that occur with aging. My lab is especially interested in understanding how exercise training reverses microvascular dysfunction that occurs with advancing age.
Sindler AL, Reyes R, Gurovich AN, Chen B, Delp MD, Kang LS, Cardounel AJ, and Muller-Delp JM . Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles. J Appl Physiol. 114:681-693, 2013.
Taylor CR, Hanna MA, Behnke BJ, John N. Stabley JN, McCullough DJ, Davis RT, Ghosh P, Papadopoulos A, Muller-Delp JM, and Delp MD. Spaceflight-Induced Alterations in Cerebral Artery Vasoconstrictor, Mechanical and Structural Properties May Contribute to Elevations in Cerebral Perfusion and Intracranial Pressure. FASEB J. 27:2282-2292, 2013.
Tumer N, Toklu HZ, Muller-Delp JM, Oktay S, Ghosh P, Strang K, Delp MD, and Scarpace P. The effects of aging on the functional and structural properties of the rat basilar artery. Physiological Reports, Vol. 2 no. e12031, DOI: 10.14814/phy2.12031, 2014.
Hanna MA, Taylor CR, Chen B, La H-S, Maraj JJ, Kilar CR, Behnke BJ, Delp MD, and Muller-Delp JM. Structural Remodeling of Coronary Resistance Arteries: Effects of Age and Exercise Training. J Appl Physiol. 117: 616-623, 2014.
Ghosh P, Mora Solis FR, Dominguez JM, Spier SA, Donato AJ, Delp MD, and Muller-Delp JM. Exercise training reverses aging-induced impairment of the myogenic response in skeletal muscle arterioles. J Appl Physiol 118:904-911, 2015.
Sofronova SI, Tarasova OS,1 Gaynullina D, Borzykh AA, Behnke BJ, Stabley JN, McCullough DJ, Mara JJ, Hanna M, Muller-Delp JM, Vinogradova OL, and Delp MD. Spaceflight on the Bion-M1 biosatellite alters cerebral artery vasomotor and mechanical properties in mice. J Appl Physiol 118:830-838, 2015.
Toklu HZ, Muller-Delp JM, Yang Z, Oktay S, Sakarya Y, Strang K, Ghosh P, Delp MD, Scarpace PJ, Wang K, and Tümer N. The functional and structural changes in the basilar artery due to overpressure blast injury. J Cerebral Blood Flow Metabolism 35(12):1950-6, 2015 doi: 10.1038/jcbfm.2015.151.