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Cell Biology & Development

Developmental mechanisms and the cellular basis of disease is a major focus of research in the Biomedical Sciences Department. This Node includes research on chromosome segregation, protein degradation, metabolism, cytoskeleton regulation, cell signaling, and transcriptional regulation.

Several groups study the development of multicellular organisms, with an emphasis on the development of the nervous system, musculoskeletal system, and reproductive tissues, among others.

 

  Michelle Arbeitman Ph.D.
Sex differences in development and behavior.

  Pradeep Bhide Ph.D.
Developmental neurological and psychiatric conditions including ADHD and early-onset generalized dystonia.

Akash Gunjan Ph.D.
Role of histones in genome stability and cancer.

  Jamila I Horabin Ph.D.
Long non-coding RNAs, RNA silencing and chromatin modifiers in regulating Drosophila sex determination.

Myra M Hurt Ph.D.
Molecular regulation of the cell division cycle.

  Daniel L Kaplan Ph.D.
DNA replication and cancer.

  Yoichi Kato, M.D., Ph.D.
The role of notch signaling in ciliogenesis and early neural development.

  Choogon Lee Ph.D.
Molecular basis for circadian rhythms.

  David Meckes Ph.D.
Molecular pathogenesis of Epstein-Barr Virus-associated cancers.

  Timothy Megraw Ph.D.
The functions of centrosomes and cilia in cell division, development and disease.

  Richard S Nowakowski Ph.D.
Cell cycle and neurogenesis in the developing adult nervous system; genetics of individual variation in the brain of mouse and man.

James Olcese Ph.D.
Neuroendocrine chronobiology and reproductive neuroscience.

Gregg Stanwood Ph.D.
The developmental basis of mental health disorders.

  Branko Stefanovic Ph.D.
Molecular mechanisms of liver fibrosis.

  Robert J Tomko Jr. Ph.D.
Regulation of proteasome assembly and function in health and disease; design principles governing assembly of multiprotein complexes.

  Yuan Wang Ph.D.
Development and plasticity of neuronal circuits and their pathology in neurodevelopmental disorders and neurodegeneration.

  Yanchang Wang Ph.D.
Chromosome segregation regulation and the response to the expression of misfolded protein.